2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer.


Few therapeutic treatment options are available for patients suffering from metastatic androgen-independent prostate cancer. We investigated the ability of the estrogen metabolite 2-methoxyestradiol to inhibit the proliferation of a variety of human prostate cancer cell lines in vitro and to inhibit the growth of androgen-independent prostate cancer in a… (More)


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@article{Qadan20012MethoxyestradiolIG, title={2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer.}, author={Laila Rafiq Qadan and C Perez-stable and Chance Anderson and Gianluca D'Ippolito and Alan J. Herron and Guy A. Howard and Bernard A. Roos}, journal={Biochemical and biophysical research communications}, year={2001}, volume={285 5}, pages={1259-66} }