2 Imbalance of Prevalence and Specialty Care for First Nations with Osteoarthritis in


Objective: The main cause of lethality in the autoimmune connective tissue disease scleroderma is organ fibrosis. Cellular behavior is altered by their local microenvironment, which includes enhanced local stimulation of mechanical signaling pathways. Fibrotic lesions are, by their nature, characterized by significantly enhanced mechanical forces relative… (More)