2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

@inproceedings{MarcillaEtxenike20122HydroxyoleicAI,
  title={2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines},
  author={Amaia Marcilla-Etxenike and Maria Laura Mart{\'i}n and Maria Ant{\`o}nia Noguera-Salv{\`a} and Jose Manuel Garc{\'i}a-Verdugo and Mario Soriano-Navarro and Indranil Dey and Pablo V. Escrib{\'a} and Xavier Busquets},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND 2-Hydroxyoleic acid is a synthetic fatty acid with potent anti-cancer activity which does not induce undesired side effects. However, the molecular and cellular mechanisms by which this compound selectively kills human glioma cancer cells without killing normal cells is not fully understood. The present study was designed to determine the molecular bases underlying the potency against 1321N1, SF-767 and U118 human glioma cell lines growth without affecting non cancer MRC-5 cells… CONTINUE READING
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