2-Hydroxy-3-methoxybenzoic acid attenuates mast cell-mediated allergic reaction in mice via modulation of the FcεRI signaling pathway

@inproceedings{Kim20172Hydroxy3methoxybenzoicAA,
  title={2-Hydroxy-3-methoxybenzoic acid attenuates mast cell-mediated allergic reaction in mice via modulation of the FcεRI signaling pathway},
  author={Yeon-Yong Kim and In-Gyu Je and Min Jong Kim and Byeong-Cheol Kang and Moon-Chang Baek and Byungheon Lee and Jin Kyeong Choi and Hae Ran Park and Tae-Yong Shin and Soyoung Lee and Seung-Bin Yoon and Sang-Rae Lee and Dongwoo Khang and S. E. Kim},
  booktitle={Acta Pharmacologica Sinica},
  year={2017}
}
Mast cells are important effector cells in immunoglobulin (Ig) E-mediated allergic reactions such as asthma, atopic dermatitis and rhinitis. Vanillic acid, a natural product, has shown anti-oxidant and anti-inflammatory activities. In the present study, we investigated the anti-allergic inflammatory effects of ortho-vanillic acid (2-hydroxy-3-methoxybenzoic acid, o-VA) that was a derivative of vanillic acid isolated from Amomum xanthioides. In mouse anaphylaxis models, oral administration of o… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

Elaeocarpusin Inhibits Mast Cell-Mediated Allergic Inflammation

  • Front. Pharmacol.
  • 2018
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

The Cell Research Trends of Asthma: A Stem Frequency Analysis of the Literature

  • Journal of healthcare engineering
  • 2018
VIEW 2 EXCERPTS
CITES METHODS

References

Publications referenced by this paper.
SHOWING 1-10 OF 44 REFERENCES

Similar Papers

Loading similar papers…