2-D DIGE analysis of liver and red blood cells provides further evidence for oxidative stress in schizophrenia.

@article{Prabakaran20072DDA,
  title={2-D DIGE analysis of liver and red blood cells provides further evidence for oxidative stress in schizophrenia.},
  author={Sudhakaran Prabakaran and Martina Wengenroth and Helen E. Lockstone and Kathryn S. Lilley and F. Markus Leweke and Sabine Bahn},
  journal={Journal of proteome research},
  year={2007},
  volume={6 1},
  pages={141-9}
}
The molecular disease mechanisms associated with schizophrenia remain largely unknown. Although primarily considered a disorder of the brain, there is evidence of a peripheral component to schizophrenia. In this study, we investigated liver tissue and red blood cells (RBC) from schizophrenia patients and controls using 2-D DIGE proteomic analysis. Fourteen proteins were significantly altered in liver samples from schizophrenia patients (n = 15) compared to healthy controls (n = 15). Analysis of… CONTINUE READING
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