2-Chlorodeoxyadenosine therapy in Waldenstrom's macroglobulinaemia.

@article{Delannoy19942ChlorodeoxyadenosineTI,
  title={2-Chlorodeoxyadenosine therapy in Waldenstrom's macroglobulinaemia.},
  author={Andr{\'e} Delannoy and Augustin Ferrant and Philippe Martiat and Andr{\'e} Bosly and A. Zenebergh and Jean Louis Michaux},
  journal={Nouvelle revue francaise d'hematologie},
  year={1994},
  volume={36 4},
  pages={317-20}
}
Despite some encouraging first results, experience with 2-chlorodeoxyadenosine (CdA) in the treatment of Waldenström's macroglobulinaemia (WM) has not as yet been very extensive. The present paper reports a clinical trial of the use of CdA in 18 patients having previously treated (n = 13) or untreated (n = 5) WM. CdA was administered by continuous intravenous infusion at a dose of 4 mg/m2/day for 7 days (5 patients) or as 2-h intravenous infusions at a dose of 5.6 mg/m2/day for 5 days (13… CONTINUE READING

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