2-(2-phenylethyl)chromone derivatives in Chinese agarwood "Qi-Nan" from Aquilaria sinensis.

  title={2-(2-phenylethyl)chromone derivatives in Chinese agarwood "Qi-Nan" from Aquilaria sinensis.},
  author={De-Lan Yang and Wenli Mei and Yanbo Zeng and Zhi-kai Guo and You-Xing Zhao and Hao Wang and Wen-jian Zuo and Wenhua Dong and Qing Huang Wang and Haofu Dai},
  journal={Planta medica},
  volume={79 14},
Five new 2-(2-phenylethyl)chromone derivatives, qinanones A-E (1-5), together with eight known 2-(2-phenylethyl)chromone derivatives (6-13), were isolated from the Et2O extract of high-quality Chinese agarwood "Qi-Nan" originating from Aquilaria sinensis. The structures of the new 2-(2-phenylethyl)chromones were elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR) and MS analyses. In the bioassay for acetylcholinesterase inhibitors, compounds 1-6, 10, and 12 exhibited weak inhibitory… 
A new 2-(2-phenylethyl)chromone glycoside in Chinese agarwood “Qi-Nan” from Aquilaria sinensis
The structure including the absolute configuration of the sugar moiety was elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR), MS analysis, PMP-labeling HPLC analysis methods, as well as comparison with literature data.
Two new 2-(2-Hydroxy-2-phenylethyl)chromens from agarwood originating from Aquilaria crassna
Two new 2-(2-hydroxy-2-phenylethyl)chromones (1‒2), along with three known 2-(3‒5), were isolated from the agarwood originating from Aquilaria crassna Pierre ex Lecomte and determined by the spectroscopic methods including 1D and 2D NMR analysis and comparison with reported data in the literature.
Three New 2-(2-Phenylethyl)chromone Derivatives of Agarwood Originated from Gyrinops salicifolia
Two new 2-(2-phenylethyl)chromone derivatives (1–2) were isolated from the ethyl acetate extraction of agarwood originated from Gyrinops salicifolia Ridl and all structures were unambiguously elucidated on the basis of 1D and 2D NMR spectra as well as by HRESIMS data.
2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia
Three new 2-(2-phenylethyl)chromone derivatives (1, 2, and 5) showed moderate cytotoxicity against human tumor K562, BEL-7402, and SGC-7901 cell lines with IC50 values of 5.76 to 20.1 µM.
2-(2-Phenylethyl)chromone derivatives in artificial agarwood from Aquilaria sinensis.
New 2-(2-phenylethyl)chromone derivatives from agarwood and their inhibitory effects on tumor cells
Two new chromone derivatives were isolated from the EtOH extract of agarwood of Aquilaria sinensis, together with eleven known analogues, and showed weak cytotoxic activities with IC50 values ranged from 18.82 to 37.95 µg/ml.
Analysis of 2-(2-Phenylethyl)chromones by UPLC-ESI-QTOF-MS and Multivariate Statistical Methods in Wild and Cultivated Agarwood
Results indicated that UPLC–ESI-QTOF-MS-based metabonomics analysis in agarwood may be useful for distinguishing wild agar wood from cultivated agarwoods.
Characterization and Analysis of 2-(2-Phenylethyl)-chromone Derivatives from Agarwood (Aquilaria crassna) by Artificial Holing for Different Times
The characteristic fragmentation behavior of DEPECs and EPECs, and the methods to distinguish these four types of chromones by MS analysis were described for the first time and could be referenced to distinguish different agarwood samples collected from different formation time.