2‐Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal‐cannabidiol‐sensitive receptors on microglial cells

@article{Kreutz20092ArachidonoylglycerolEN,
  title={2‐Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal‐cannabidiol‐sensitive receptors on microglial cells},
  author={Susanne Kreutz and M. Koch and Charlotte B{\"o}ttger and C. Ghadban and H. Korf and F. Dehghani},
  journal={Glia},
  year={2009},
  volume={57}
}
Endocannabinoids like 2‐arachidonoylglycerol (2‐AG) exert neuroprotective effects after brain injuries. According to current concepts, these neuroprotective effects are due to interactions between 2‐AG and cannabinoid (CB)1 receptors on neurons. Moreover, 2‐AG modulates migration and proliferation of microglial cells which are rapidly activated after brain lesion. This effect is mediated via CB2‐ and abnormal‐cannabidiol (abn‐CBD)‐sensitive receptors. In the present study, we investigated… Expand
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