2,6,9-trisubstituted purines: optimization towards highly potent and selective CDK1 inhibitors.

@article{Imbach1999269trisubstitutedPO,
  title={2,6,9-trisubstituted purines: optimization towards highly potent and selective CDK1 inhibitors.},
  author={Patricia Imbach and Hans-Georg Capraro and Pascal Furet and Helmut Mett and Thomas Meyer and Johann Georg Zimmermann},
  journal={Bioorganic & medicinal chemistry letters},
  year={1999},
  volume={9 1},
  pages={91-6}
}
Novel 2,6,9-substituted purine derivatives represent a class of potent and selective inhibitors of CDK1/cyclinB. The synthesis, SAR and biological profile of selected compounds are described. 

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