2,5-Hexanedione-induced accumulations of neurofilament-immunoreactive material throughout the rat autonomic nervous system.

@article{Ferri198825HexanedioneinducedAO,
  title={2,5-Hexanedione-induced accumulations of neurofilament-immunoreactive material throughout the rat autonomic nervous system.},
  author={Gian Luca Ferri and S. Zareh and Alberto Amadori and Antonio Bastone and Maria Sbraccia and D G Dahl and N. Frontali},
  journal={Brain research},
  year={1988},
  volume={444 2},
  pages={383-8}
}
In rats intoxicated with 2,5-hexanedione, nerve fibres supplying virtually all visceral organs showed large numbers of densely immunoreactive accumulations of neurofilament-like material, of fusiform, elongated, smoothly tapering morphology. In the gut, round to oval, morphologically different lesions were also present, and abnormal neurofilament-immunoreactive accumulations were revealed in oesophageal terminal end-plates. An extensive damage to autonomic nerve fibres, which are largely non… CONTINUE READING

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