2,5-Diaryloxadiazoles and their precursors as novel inhibitors of cathepsins B, H and L.

Abstract

High levels of cathepsins indicated in various pathological conditions like arthritis, cancer progressions, and atherosclerosis explains the need to explore potential inhibitors of these proteases which can be of great therapeutic significance. We, in the present work, report the synthesis of some 2,5-diaryloxadiazoles from N… (More)
DOI: 10.1016/j.bioorg.2016.05.003

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