2,2'-Dithienyl diselenide pro-oxidant activity accounts for antibacterial and antifungal activities.

@article{Pesarico201322DithienylDP,
  title={2,2'-Dithienyl diselenide pro-oxidant activity accounts for antibacterial and antifungal activities.},
  author={A. Pesarico and G. Sartori and C. F. D. dos Santos and Jose S S Neto and V. Bortolotto and R. C. Santos and C. W. Nogueira and M. Prigol},
  journal={Microbiological research},
  year={2013},
  volume={168 9},
  pages={
          563-8
        }
}
The aim of this study was to explore if 2,2'-dithienyl diselenide (DTDS) pro-oxidant activity is related to its antibacterial and antifungal actions. The antimicrobial activity of DTDS against bacterial and fungal was investigated in the broth microdilution assay (3.02-387 μg/ml). Additionally, the survival curve of microorganisms in the presence of DTDS (12.09-193.5 μg/ml) was performed. The involvement of pro-oxidant activity in the DTDS antimicrobial action was investigated by supplementing… Expand
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