2,2′-dithienyl diselenide, an organoselenium compound, elicits antioxidant action and inhibits monoamine oxidase activity in vitro

@article{Bortolatto201322dithienylDA,
  title={2,2′-dithienyl diselenide, an organoselenium compound, elicits antioxidant action and inhibits monoamine oxidase activity in vitro},
  author={C. F. Bortolatto and P. M. Chagas and E. A. Wilhelm and G. Zeni and C. W. Nogueira},
  journal={Journal of Enzyme Inhibition and Medicinal Chemistry},
  year={2013},
  volume={28},
  pages={677 - 684}
}
Context: Organoselenium compounds have been described as antioxidant and neuroprotective agents. Objective: To evaluate the antioxidant action of 2,2′-dithienyl diselenide (DTDS) and its effects in brain monoamine oxidase (MAO) activity in vitro. Materials and methods: Assays for reactive species (RS), lipid peroxidation, protein oxidation, MAO A and B activities in rat brain homogenate as well as mimetic dehydroascorbate reductase and glutathione S-transferase activities were performed using… Expand
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