2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy.

@article{Chen201027DichlorodihydrofluoresceinAA,
  title={2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy.},
  author={Xiao-jia Chen and Zhangfeng Zhong and Zengtao Xu and Lidian Chen and Yitao Wang},
  journal={Free radical research},
  year={2010},
  volume={44 6},
  pages={587-604}
}
Reactive oxygen species (ROS) are critically important chemical intermediates in biological studies, due to their multiple physiologically essential functions and their often pathologically deleterious effects. Consequently, it is vital that their presence in biological samples has to be quantifiable. However, their high activity, very short life span and extremely low concentrations make ROS measurement a scientifically challenging subject for researchers. One of the widespread methods for ROS… CONTINUE READING

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