1alpha,25-dihydroxy-vitamin D3 in combination with 17beta-estradiol lowers the cortical expression of heat shock protein-27 following experimentally induced focal cortical ischemia in rats.

Abstract

1alpha,25-(OH)(2)-vitamin-D(3) (1,25-D(3)) and 17beta-estradiol are both known to act neuroprotective in certain experimental in vitro and in vivo settings. We studied the effects of 1,25-D(3) or 17beta-estradiol or their combined application on heat shock protein-27 (HSP-27) distribution after focal cortical ischemia using the photothrombosis model. HSP-27… (More)

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@article{LosemHeinrichs20051alpha25dihydroxyvitaminDI, title={1alpha,25-dihydroxy-vitamin D3 in combination with 17beta-estradiol lowers the cortical expression of heat shock protein-27 following experimentally induced focal cortical ischemia in rats.}, author={Eva Losem-Heinrichs and Boris G{\"o}rg and Christoph Redecker and Axel Schleicher and Otto W. Witte and Karl Zilles and Hans-J. Bidmon}, journal={Archives of biochemistry and biophysics}, year={2005}, volume={439 1}, pages={70-9} }