1H-NMRD and17O-NMR assessment of water exchange and rotational dynamics of two potential MRI agents: MP-1177 (an extracellular agent) and MP-2269 (a blood pool agent)

@article{Adzamli20071HNMRDAA,
  title={1H-NMRD and17O-NMR assessment of water exchange and rotational dynamics of two potential MRI agents: MP-1177 (an extracellular agent) and MP-2269 (a blood pool agent)},
  author={K. Adzamli and E. T{\'o}th and M. Periasamy and S. H. Koenig and A. E. Merbach and M. Adams},
  journal={Magnetic Resonance Materials in Physics, Biology and Medicine},
  year={2007},
  volume={8},
  pages={163-171}
}
  • K. Adzamli, E. Tóth, +3 authors M. Adams
  • Published 2007
  • Medicine
  • Magnetic Resonance Materials in Physics, Biology and Medicine
  • The parameters that govern water proton magnetic relaxation (e.g. water exchange rates, and rotational and electronic correlation times) of representatives of two classes of Gd(III) complexes have been estimated, using two different approaches and the results compared with those derived for known analogs. The complexes studied are: (i) the non-ionic GdDTPA-bis(methoxyethyl-amide) [Gd(DTPA-BMEA)], a typical small-molecule extracellular MR agent, and (ii) the ionic Gd(III) complex of 4… CONTINUE READING
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