1H NMR-based metabolomic study on resistance to diet-induced obesity in AHNAK knock-out mice.

@article{Kim20101HNM,
  title={1H NMR-based metabolomic study on resistance to diet-induced obesity in AHNAK knock-out mice.},
  author={Il Yong Kim and Jeeyoun Jung and Mi So Jang and Yun Gyong Ahn and Jae Hoon Shin and Ji Won Choi and Mi Ra Sohn and Sun Mee Shin and Dae Gill Kang and H S Lee and Yun Soo Bae and Do Hyun Ryu and Je Kyung Seong and G. T. Gene Hwang},
  journal={Biochemical and biophysical research communications},
  year={2010},
  volume={403 3-4},
  pages={428-34}
}
AHNAK is a giant protein of approximately 700 kDa identified in human neuroblastomas and skin epithelial cells. Recently, we found that AHNAK knock-out (AHNAK(-/-)) mice have a strong resistance to high-fat diet-induced obesity. In this study, we applied (1)H NMR-based metabolomics with multivariate statistical analysis to compare the altered metabolic… CONTINUE READING