1H MR spectroscopy in the assessment of gliomatosis cerebri.

@article{GuzmnDeVilloria20071HMS,
  title={1H MR spectroscopy in the assessment of gliomatosis cerebri.},
  author={Juan Adan Guzm{\'a}n-De-Villoria and Javier Sanchez-Gonz{\'a}lez and Luc{\'i}a Mu{\~n}oz and Santiago Reig and Carlos Benito and Pedro Garc{\'i}a-Barreno and Manuel Desco},
  journal={AJR. American journal of roentgenology},
  year={2007},
  volume={188 3},
  pages={
          710-4
        }
}
OBJECTIVE Gliomatosis cerebri is a rare brain tumor with a short survival time; for this reason, it is difficult to establish the degree of aggressivity in vivo. The MR spectroscopic findings on this tumor often do not agree with choline level. The purpose of this study was to evaluate whether MR spectroscopy can be used to measure tumor choline levels and whether the findings give useful information about tumor growth rate and patient survival time. SUBJECTS AND METHODS We performed MRI and… 
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35 Citations
Background Citations
7
Methods Citations
2

35 Citations

Citation Type

Citation Type

1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
TLDR
Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.
Gliomatosis cerebri, imaging findings of 12 cases.
Clinical, neuroimaging and histopathological features of gliomatosis cerebri: a systematic review based on synthesis of published individual patient data
TLDR
A distinct clinical, neuroimaging, histopathological, or molecular GC phenotype is not supported by current evidence, and MRI and MR spectroscopy are important tools for the diagnosis of the tumor before confirmation with biopsy.
Gliomatosis cerebri type 1 mimicking an ischemic stroke and progressing to a type 2: a case study and literature review.
ABSTRACT Aims: To report a rare clinical case of gliomatosis cerebri, which presented with non-specific clinical, laboratory, and radiological findings. We provide images and stress theimportance of…
Lack of choline elevation on proton magnetic resonance spectroscopy in grade I–III gliomas
TLDR
The findings suggest that a lack of choline/creatine or ch Caroline/water elevation may be seen in some gliomas and low choline levels should not prevent us from considering the possibility of a grade I–III glioma.
Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases
TLDR
Poor survival showed correlation with higher Ki-67 labeling index, higher choline/N-acetylaspartate ratio on magnetic resonance spectroscopy, tumor volumes, lower Karnofsky performance status on admission, cognitive/behavioral deterioration, poor response to the initial radiochemotherapy, and emergence of paraventricular enhanced lesions during the clinical course.
Gliomatosis Cerebri: A Review
TLDR
The evaluation of histologic data together with clinical and radiologic features, performance status, and molecular profile may be of help and the evaluation of advanced of magnetic resonance imaging and positron emission tomography techniques to predict outcome and monitoring the treatment still remains to be defined.
Prognostic Factors and Survival of Gliomatosis Cerebri: A Systematic Review and Meta-Analysis.
Incidence and survival of gliomatosis cerebri: a population-based cancer registration study
TLDR
This first comprehensive overview of GC epidemiology exemplifies the rarity of the disease, provides evidence for male preponderance and increased incidence among the elderly and shows lower survival rates compared to the published single center reports.
¹¹C-Methionine or ¹¹C-Choline PET is superior to MRI in the evaluation of gliomatosis cerebri.
TLDR
These findings show that multiple tracer PET might not only reflect the true extent of GC infiltration but also evaluate GC malignant processes more accurately than MRI.
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References

SHOWING 1-10 OF 22 REFERENCES
MR spectroscopy in gliomatosis cerebri.
TLDR
MR spectroscopy might be used to classify gliomatosis cerebri as a stable or a progressive disease indicating its potential therapeutic relevance.
Use of proton magnetic resonance spectroscopy of the brain to differentiate gliomatosis cerebri from low-grade glioma.
TLDR
Owing to the unfavorable clinical outcome associated with GC compared with that associated with LGG, the findings of this study illustrate the diagnostic and prognostic value of proton MR spectroscopy in the characterization of infiltrating gliomas.
Proton Magnetic Resonance Spectroscopic Imaging Can Predict Length of Survival in Patients with Supratentorial Gliomas
TLDR
It is suggested that appropriate analysis of 1H-MRSI data can predict survival in patients with supratentorial gliomas at least as accurately as data derived from more invasive clinicopathological features.
Gliomatosis cerebri: comparison of MR and CT features.
TLDR
MR imaging is more sensitive than CT for detecting lesions and shows the extent of disease better than CT does, and should be used as a primary imaging study in the evaluation of gliomatosis cerebri.
Proton MR spectroscopy of gliomatosis cerebri: case report of elevated myoinositol with normal choline levels.
TLDR
In suspected cases of gliomatosis cerebri, myo-inositol/creatine and myo/N-acetyl should be determined because they may provide evidence of tumor, even though choline/Creatine is normal.
Gliomatosis cerebri
A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas.
TLDR
The pretreatment spectroscopic results provided information that was predictive of outcome for this patient pool, both in local control and global outcome, and this modality may have an important role in improving the selection, planning, and treatment process for glioma patients.
Diagnosis and management of gliomatosis cerebri: recent trends.
Gliomatosis cerebri: clinical and histological findings.
TLDR
The clinical and pathological data of ten patients with gliomatosis cerebri are compared with 48 well documented cases from the literature and it is suggested that this disease might be the result of propagation of initiated glial elements which have not yet undergone the process of tumor conversion.
Characterization of untreated gliomas by magnetic resonance spectroscopic imaging.
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