1H-MR spectroscopic detection of metabolic changes in pain processing brain regions in the presence of non-specific chronic low back pain

@article{Gussew20111HMRSD,
  title={1H-MR spectroscopic detection of metabolic changes in pain processing brain regions in the presence of non-specific chronic low back pain},
  author={Alexander Gussew and Reinhard Rzanny and Daniel G{\"u}llmar and Hans-Christoph Scholle and J{\"u}rgen R. Reichenbach},
  journal={NeuroImage},
  year={2011},
  volume={54 2},
  pages={1315-23}
}
Reliable detection of metabolic changes in the brain in vivo induced by chronic low back pain may provide improved understanding of neurophysiological mechanisms underlying the manifestation of chronic pain. In the present study, absolute concentrations of N-acetyl-aspartate (NAA), creatine (Cr), total choline (tCho), myo-inositol (mI), glutamate (Glu) and glutamine (Gln) were measured in three different pain processing cortical regions (anterior insula, anterior cingulate cortex, and thalamus… CONTINUE READING

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