19F nuclear magnetic resonance as a probe of the spatial relationship between the heme iron of cytochrome P-450 and its substrate.

Abstract

The distance between the heme iron of ferrous cytochrome P-450-CAM and a fluorine label attached to the 9-methyl carbon of its substrate, (1R)-(+)-camphor, has been determined using 19F NMR. This investigation uses the Solomon-Bloembergen equation to measure the distance from a paramagnetic heme iron to a fluorine probe incorporated into a substrate that is… (More)

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@article{Crull198919FNM, title={19F nuclear magnetic resonance as a probe of the spatial relationship between the heme iron of cytochrome P-450 and its substrate.}, author={G B Crull and Jeff Kennington and A. Garber and Paul D. Ellis and John H. Dawson}, journal={The Journal of biological chemistry}, year={1989}, volume={264 5}, pages={2649-55} }