18F-FLT PET/CT imaging in a Wister rabbit inflammation model

  title={18F-FLT PET/CT imaging in a Wister rabbit inflammation model},
  author={Yeying Tan and Jun Liang and Defeng Liu and Feng Zhu and Guanmin Wang and X. M. Ding and Conghui Han},
  booktitle={Experimental and therapeutic medicine},
The aim of the present study was to determine the tumour specificity of the newly developed nucleoside metabolic positron emission tomography (PET) tracer, 3'-deoxy-3'-18F-fluorothymidine (18F-FLT). Using 18F-FLT PET imaging, DNA synthesis and cell proliferation were detected in Staphylococcus aureus (S. aureus) abscess and calcium sulphate models in Wister rabbits. A total of eight rabbits were implanted with S. aureus in the left tibia to induce an inflammatory process. Calcium sulphate… CONTINUE READING


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