18F-FAC PET selectively images hepatic infiltrating CD4 and CD8 T cells in a mouse model of autoimmune hepatitis.

@article{Salas201818FFACPS,
  title={18F-FAC PET selectively images hepatic infiltrating CD4 and CD8 T cells in a mouse model of autoimmune hepatitis.},
  author={Jessica R Salas and Bao Ying Chen and Alicia Wong and Donghui Cheng and John S. Van Arnam and Owen N Witte and Peter R. Clark},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2018}
}
Immune cell-mediated attack on the liver is a defining feature of autoimmune hepatitis and hepatic allograft rejection. Despite an assortment of diagnostic tools, invasive biopsies remain the only method for identifying immune cells in the liver. We evaluated whether PET imaging with radiotracers that quantify immune activation (18F-FDG and 18F-FAC) and… CONTINUE READING