18 kDa protein tyrosine phosphatase in the ocular lens.

  title={18 kDa protein tyrosine phosphatase in the ocular lens.},
  author={I Ogihara Umeda and Yasuhiro Kashiwa and Hideo Nishigori},
  journal={Experimental eye research},
  volume={73 1},
Protein tyrosyl phosphorylation and dephosphorylation play essential roles in regulating cellular events such as proliferation and differentiation, and their involvement in the lens development and transparency is also suggested. The level of tyrosine phosphorylation in a given protein is regulated by the opposing actions of protein-tyrosine kinases (Tyr kinases) and protein-tyrosine phosphatases (TyrPases). Recent studies have revealed that some Tyr kinases, such as platelet-derived growth… CONTINUE READING