17p13.3 microduplication, a potential novel genetic locus for nonsyndromic bilateral cleft lip and palate.

@article{Ibitoye201517p133MA,
  title={17p13.3 microduplication, a potential novel genetic locus for nonsyndromic bilateral cleft lip and palate.},
  author={Rita Ibitoye and Joanna D. Roberts and Tim Goodacre and U. D. Kini},
  journal={The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association},
  year={2015},
  volume={52 3},
  pages={359-62}
}
Cleft lip and palate (CLP) is a relatively common congenital malformation. The etiology is complex and postulated to be a combination of genetic and environmental factors. The genetic loci for nonsyndromic CLP remain poorly characterized. Two families have recently been reported with a chromosome 17p13.3 microduplication and CLP. We report a third family… CONTINUE READING