17Beta-hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female patients with colon cancer.

Abstract

The mRNA expression of 17beta-hydroxysteroid dehydrogenase (17HSD) types 1 and 2 enzymes catalyzing opposite reaction of estrogen metabolism was investigated in colon cancer. Further, the significance of the 17HSD type 2 enzyme as a possible marker of colorectal cancer (CRC) prognosis was studied. In the normal mucosa, 17HSD type 2 mRNA was predominantly… (More)

Topics

Cite this paper

@article{Oduwole200317BetahydroxysteroidDT, title={17Beta-hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female patients with colon cancer.}, author={Olayiwola O. Oduwole and Markus J. M{\"a}kinen and Veli V Isomaa and Anitta E. Pulkka and Petra Jernvall and Tuomo Juhani Karttunen and Pirkko T. Vihko}, journal={The Journal of steroid biochemistry and molecular biology}, year={2003}, volume={87 2-3}, pages={133-40} }