17Beta-estradiol affects the response of complement components and survival of rainbow trout (Oncorhynchus mykiss) challenged by bacterial infection.

@article{Wenger201117BetaestradiolAT,
  title={17Beta-estradiol affects the response of complement components and survival of rainbow trout (Oncorhynchus mykiss) challenged by bacterial infection.},
  author={Michael Wenger and Ursula Sattler and Elinor Goldschmidt-Clermont and Helmut Segner},
  journal={Fish & shellfish immunology},
  year={2011},
  volume={31 1},
  pages={90-7}
}
Research on the endocrine role of estrogens has focused on the reproductive system, while other potential target systems have been less studied. Here, we investigated the possible immunomodulating role of 17β-estradiol (E2) using rainbow trout (Oncorhynchus mykiss) as a model. The aims of the study were to examine a) whether estrogens can modulate immune gene transcription levels, and b) whether this has functional implications for the resistance of trout towards pathogens. Trout were reared… CONTINUE READING

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