1717 MITOCHONDRIAL RESPIRATORY ACTIVITY: RESPONSE TO INCREASED CARBOXYHEMOGLOBIN (COHb) IN BRAIN AND HEART OF GUINEA PIGS

Abstract

Previous studies show that mitochondria adapt to changes of arterial PO2. The present study investigates heart and brain mitochondrial respiratory rate (RR) in 23 guinea pigs at varying blood COHb levels. Blood gases and [COHb] were recorded in all animals. Brain and heart mitochondria were isolated. State 4 RR, state 3 RR with glutamate-malate substrate… (More)
DOI: 10.1203/00006450-198104001-01736

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@article{Sacks19811717MR, title={1717 MITOCHONDRIAL RESPIRATORY ACTIVITY: RESPONSE TO INCREASED CARBOXYHEMOGLOBIN (COHb) IN BRAIN AND HEART OF GUINEA PIGS}, author={Linda M Sacks and David Herbert and Crosby Roper and Thomas P Heffernan and Mar{\'i}a Delivoria-Papadopoulos}, journal={Pediatric Research}, year={1981}, volume={15}, pages={729-729} }