17 beta-oestradiol counteracts the formation of the more acidic isoforms of follicle-stimulating hormone and luteinizing hormone after menopause.

@article{Wide199417BC,
  title={17 beta-oestradiol counteracts the formation of the more acidic isoforms of follicle-stimulating hormone and luteinizing hormone after menopause.},
  author={Leif Wide and Tord Naess{\'e}n},
  journal={Clinical endocrinology},
  year={1994},
  volume={40 6},
  pages={783-9}
}
OBJECTIVE When the gonadotrophin levels increase at midcycle, more basic isoforms of FSH and LH appear in the circulation. However, when these gonadotrophins increase at menopause more acidic forms appear. The present study was done to see whether chronic 17 beta-oestradiol (E2) administration to post-menopausal women could counteract the formation of the more acidic isoforms after the menopause. DESIGN Serum samples were obtained from 16 post-menopausal women, mean age 70 years (range 63-84… CONTINUE READING