17-P019 A Pax3/7:Foxc2 negative feedback loop in the somite modulates multipotent stem cell fates

mordial germ cells (PGCs) in mice and axolotls, we propose that the deletion of Nanog in species often employed as experimental models, such as frogs and teleosts (Zebrafish; Danio rerio), has been compensated by the evolution of predetermined germ cells in these organisms. Our data highlights Nanog as a major component of the gene regulatory network that… CONTINUE READING