Corpus ID: 27129026

17 Dithiocarbamate Toxicity-An Appraisal

@inproceedings{Rath201217DT,
  title={17 Dithiocarbamate Toxicity-An Appraisal},
  author={N. Rath and K. Rasaputra and Rohana Liyanage and G. Huff and W. Huff},
  year={2012}
}
Dithiocarbamates (DTC) are organosulfur compounds represented by a general structure (R1R2)N-(C=S)-SX, where R can be substituted by an alkyl, alkylene, aryl, or similar other group, and X usually by a metal ion (Edwards, 1991; Kamrin, 1997; US EPA, 2001). Discovered in the 1930s, the DTC were first introduced as fungicides for commercial applications during World War II (Ware & Whitacre, 2004). Besides their wide use as fungicides for treatment of crops, vegetables, seeds, and ornamental… Expand

Figures from this paper

References

SHOWING 1-10 OF 114 REFERENCES
Nitrogen substituent polarity influences dithiocarbamate-mediated lipid oxidation, nerve copper accumulation, and myelin injury.
  • 18
Catalysis of catechol oxidation by metal-dithiocarbamate complexes in pesticides.
  • 78
Evaluation of the aneugenic potential of the fungicide Ferbam in mice.
  • 4
The effects of the endocrine disruptors dithiocarbamates on the mammalian ovary with particular regard to mancozeb.
  • 47
Dithiocarbamate toxicity toward thymocytes involves their copper-catalyzed conversion to thiuram disulfides, which oxidize glutathione in a redox cycle without the release of reactive oxygen species.
  • 116
  • Highly Influential
Dithiocarbamates have a common toxic effect on zebrafish body axis formation.
  • 65
Pyrrolidine dithiocarbamate induces cyclooxygenase-2 expression in NIH 3T3 fibroblast cells.
  • J. E. Lee, K. Kim, +9 authors W. Baek
  • Chemistry, Medicine
  • Biochemical and biophysical research communications
  • 2002
  • 8
Characterization of isothiocyanates, thioureas, and other lysine adduction products in carbon disulfide-treated peptides and protein.
  • 12
Developmental toxicity of the dithiocarbamate pesticide sodium metam in zebrafish.
  • 89
  • PDF
Ethylenebisdithiocarbamates and ethylenethiourea: possible human health hazards.
  • 102
  • Highly Influential
  • PDF
...
1
2
3
4
5
...