17-β estradiol increases parvalbumin levels in Pvalb heterozygous mice and attenuates behavioral phenotypes with relevance to autism core symptoms

@inproceedings{Filice201817EI,
  title={17-β estradiol increases parvalbumin levels in Pvalb heterozygous mice and attenuates behavioral phenotypes with relevance to autism core symptoms},
  author={Federica Filice and Emanuel Lauber and Karl Jakob V{\"o}rckel and Markus W{\"o}hr and Beat Schwaller},
  booktitle={Molecular autism},
  year={2018}
}
Background Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by two core symptoms: impaired social interaction and communication, and restricted, repetitive behaviors and interests. The pathophysiology of ASD is not yet fully understood, due to a plethora of genetic and environmental risk factors that might be associated with or causal for ASD. Recent findings suggest that one putative convergent pathway for some forms of ASD might be the downregulation of… CONTINUE READING
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