16S rRNA gene sequencing and healthy reference ranges for 28 clinically relevant microbial taxa from the human gut microbiome

@article{Almonacid201716SRG,
  title={16S rRNA gene sequencing and healthy reference ranges for 28 clinically relevant microbial taxa from the human gut microbiome},
  author={Daniel E. Almonacid and Laurens Kraal and Francisco Ossand{\'o}n and Yelena V. Budovskaya and Juan Pablo C{\'a}rdenas and Elisabeth M. Bik and Audrey D. Goddard and Jessica Richman and Zachary S. Apte},
  journal={PLoS ONE},
  year={2017},
  volume={12}
}
Changes in the relative abundances of many intestinal microorganisms, both those that naturally occur in the human gut microbiome and those that are considered pathogens, have been associated with a range of diseases. To more accurately diagnose health conditions, medical practitioners could benefit from a molecular, culture-independent assay for the quantification of these microorganisms in the context of a healthy reference range. Here we present the targeted sequencing of the microbial 16S… Expand
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