• DOI:10.1128/AAC.42.7.1702
Corpus ID: 9143874

16S rRNA Mutation Associated with Tetracycline Resistance in a Gram-Positive Bacterium

@article{Ross199816SRM,
  title={16S rRNA Mutation Associated with Tetracycline Resistance in a Gram-Positive Bacterium},
  author={J. Ross and E. A. Eady and J. Cove and W. Cunliffe},
  journal={Antimicrobial Agents and Chemotherapy},
  year={1998},
  volume={42},
  pages={1702 - 1705}
}

J. Ross, E. A. Eady, +1 author W. Cunliffe

Published 1998

Biology, Medicine

Antimicrobial Agents and Chemotherapy

ABSTRACT A genetic basis for tetracycline resistance in cutaneous propionibacteria was suggested by comparing the nucleotide sequences of the 16S rRNA genes from 16 susceptible and 21 resistant clinical isolates and 6 laboratory-selected tetracycline-resistant mutants of a susceptible strain. Fifteen clinical isolates resistant to tetracycline were found to have cytosine instead of guanine at a position cognate with Escherichia coli 16S rRNA base 1058 in a region important for peptide chain… CONTINUE READING

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