15α-Hydroxylation of a steroid (13-ethyl-gon-4-en-3,17-dione) by Penicillium raistrickii in an ionic liquid/aqueous biphasic system

@article{Mao201215HydroxylationOA,
  title={15α-Hydroxylation of a steroid (13-ethyl-gon-4-en-3,17-dione) by Penicillium raistrickii in an ionic liquid/aqueous biphasic system},
  author={Shuhong Mao and Xiaojie Hu and Boyuan Hua and Na Wang and Xiaoguang Liu and Fuping Lu},
  journal={Biotechnology Letters},
  year={2012},
  volume={34},
  pages={2113-2117}
}
Biphasic processes are used in whole-cell biotransformation to overcome the low water solubility of substrates and products as well as their inhibitory effects on the biocatalyst. Commercially available [NTf2]- and [PF6]-based ionic liquids (ILs) were used in a biphasic system for the 15α-hydroxylation of 13-ethyl-gon-4-en-3,17-dione by Penicillium raistrickii. With the substrate at 5 g l−1 and a volume ratio of IL to buffer, buffer pH and cell density at, 1:9, 6.5, 16.8 gDW l−1, respectively… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 19 references

Use of an ionic liquid to improve asymmetric reduction of 4 0 - methoxyacetophe - none catalyzed by immobilized Rhodotorula sp . AS 2 . 2241 cells

  • W Wang, MH Zong, WY Lou
  • J Mol Catal B : Enzym
  • 2009
Highly Influential
5 Excerpts

Use of an ionic liquid to improve asymmetric reduction of 40-methoxyacetophenone catalyzed by immobilized Rhodotorula sp

  • W Wang, MH Zong, WY Lou
  • 2009
Highly Influential
7 Excerpts

Steroid hydrox

  • D Schlosser, S Irrgang, HP Schmauder
  • 1993
Highly Influential
4 Excerpts

biocatalysis with ionic liquids

  • DX Wu, YX Guan, HQ Wang, SJ Yao
  • 2011
Highly Influential
3 Excerpts

ecotoxicity EC50 (Vibrio fischeri)

  • S Oppermann, F Stein, U Kragl
  • J Mol Liq
  • 2011
2 Excerpts

Quantitative structure – activity relationships ( QSARs ) to estimate ionic liquids ecotoxicity EC 50 ( Vibrio fischeri )

  • P Luis, A Garea, A Irabien
  • J Mol Liq
  • 2010
1 Excerpt

Similar Papers

Loading similar papers…