14-Day thawed plasma retains clot enhancing properties and inhibits tPA-induced fibrinolysis.

BACKGROUND Plasma-first resuscitation attenuates trauma-induced coagulopathy (TIC); however, the logistics of plasma-first resuscitation require thawed plasma (TP) be readily available due to the obligatory thawing time of fresh frozen plasma (FFP). The current standard is storage of TP for up to 5 days at 4°C, based on factor levels at outdate, for use in… CONTINUE READING