14-3-3 proteins: a family of versatile molecular regulators.

  title={14-3-3 proteins: a family of versatile molecular regulators.},
  author={Veronika Ob{\vs}ilov{\'a} and Jan Silh{\'a}n and Evzen Boura and Jan Teisinger and Tom{\'a}{\vs} Ob{\vs}il},
  journal={Physiological research},
  volume={57 Suppl 3},
The 14-3-3 proteins are a family of acidic regulatory molecules found in all eukaryotes. 14-3-3 proteins function as molecular scaffolds by modulating the conformation of their binding partners. Through the functional modulation of a wide range of binding partners, 14-3-3 proteins are involved in many processes, including cell cycle regulation, metabolism control, apoptosis, and control of gene transcription. This minireview includes a short overview of 14-3-3 proteins and then focuses on their… CONTINUE READING