13C labeling experiments at metabolic nonstationary conditions: An exploratory study

@article{Wahl200713CLE,
  title={13C labeling experiments at metabolic nonstationary conditions: An exploratory study},
  author={Aljoscha Wahl and Katharina N{\"o}h and Wolfgang Wiechert},
  journal={BMC Bioinformatics},
  year={2007},
  volume={9},
  pages={152 - 152}
}
Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme kinetic parameters has proven to be limited with the presently available data. In metabolic flux analysis, the use of 13C labeled substrates together with isotopomer modeling solved the problem of underdetermined networks and increased the accuracy of flux estimations significantly. In this contribution, the idea of increasing… CONTINUE READING
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Simultaneous determination of multiple intracellular metabolites in glycolysis, pentose phosphate pathway and tricarboxylic acid cycle by liquid chromatography-mass spectrometry

  • B Luo, K Grönke, R Takors, C Wandrey, M Oldiges
  • J Chromatogr A
  • 2007
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