13C and 15N natural isotope abundance reflects breast cancer cell metabolism

  title={13C and 15N natural isotope abundance reflects breast cancer cell metabolism},
  author={Illa Tea and Estelle Martineau and Ingrid Antheaume and Julie Lalande and Caroline Mauve and Françoise Gilard and Sophie Barill{\'e}-Nion and Anneke C Blackburn and Guillaume Tcherkez},
  booktitle={Scientific reports},
Breast cancer is the most common cancer in women worldwide. Despite the information provided by anatomopathological assessment and molecular markers (such as receptor expression ER, PR, HER2), breast cancer therapies and prognostics depend on the metabolic properties of tumor cells. However, metabolomics have not provided a robust and congruent biomarker yet, likely because individual metabolite contents are insufficient to encapsulate all of the alterations in metabolic fluxes. Here, we took… CONTINUE READING


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