13C NMR chemical shifts can predict disulfide bond formation.

  title={13C NMR chemical shifts can predict disulfide bond formation.},
  author={Dushyant Sharma and Krishna Rajarathnam},
  journal={Journal of biomolecular NMR},
  volume={18 2},
The presence of disulfide bonds can be detected unambiguously only by X-ray crystallography, and otherwise must be inferred by chemical methods. In this study we demonstrate that 13C NMR chemical shifts are diagnostic of disulfide bond formation, and can discriminate between cysteine in the reduced (free) and oxidized (disulfide bonded) state. A database of cysteine 13C C(alpha) and C(beta) chemical shifts was constructed from the BMRB and Sheffield databases, and published journals… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 159 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 86 extracted citations

Structural characterization of CHCHD5 and CHCHD7: two atypical human twin CX9C proteins.

Journal of structural biology • 2012
View 4 Excerpts
Highly Influenced

159 Citations

Citations per Year
Semantic Scholar estimates that this publication has 159 citations based on the available data.

See our FAQ for additional information.