125I-Labelled botulinum a neurotoxin: Pharmacokinetics in cats after intramuscular injection

@article{Wiegand1976125ILabelledBA,
  title={125I-Labelled botulinum a neurotoxin: Pharmacokinetics in cats after intramuscular injection},
  author={H. J. Wiegand and Georg Erdmann and Hans H. Wellh{\"o}ner},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1976},
  volume={292},
  pages={161-165}
}
1. On unilateral injection of sublethal doses of 125I-botulinum A neurotoxin (BTA) into one gastrocnemius muscle of the cat we found after 48 h: On unilateral injection of sublethal doses of 125I-botulinum A neurotoxin (BTA) into one gastrocnemius muscle of the cat we found after 48 h: a) A disto-proximal gradient of radioactivity (RA) had developed in the sciatic nerve of the injected side. b) The ventral roots of the spinal cord half segments supplying the injected muscle showed a higher RA… CONTINUE READING
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