11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity.

  title={11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity.},
  author={Marwan Shinawi and Trilochan Sahoo and Bruno Maranda and Steven A Skinner and Cindy Skinner and Craig Chinault and Roxanne Zascavage and Sarika U Peters and Ankita Patel and Roger E Stevenson and Arthur L Beaudet},
  journal={American journal of medical genetics. Part A},
  volume={155A 6},
Genomic copy number imbalances are being increasingly identified as an important cause of intellectual disability and behavioral abnormalities. The typical deletion in WAGR syndrome encompasses the PAX6 and WT1 genes, but larger deletions have been associated with neurobehavioral abnormalities and obesity. We identified four patients with overlapping interstitial deletions on 11p14.1 and extending telomeric to the WAGR critical domain. The minimal overlapping critical chromosomal region was 2.3… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 30 extracted citations


Publications referenced by this paper.
Showing 1-10 of 49 references

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2

  • L om, N Huang, +11 authors JS. Beckmann
  • Nature
  • 2010

Similar Papers

Loading similar papers…