11C-methionine PET for differential diagnosis of low-grade gliomas.

@article{Herholz199811CmethioninePF,
  title={11C-methionine PET for differential diagnosis of low-grade gliomas.},
  author={Karl Herholz and T H{\"o}lzer and Brendan Bauer and R. K. Schroeder and J{\"u}rgen Voges and R I Ernestus and G. Indolos Mendoza and G Weber-Luxenburger and Jan L{\"o}ttgen and Alexander Thiel and Karl Wienhard and W-D Heiss},
  journal={Neurology},
  year={1998},
  volume={50 5},
  pages={1316-22}
}
Management of low-grade gliomas continues to be a challenging task, because CT and MRI do not always differentiate from nontumoral lesions. Furthermore, tumor extent and aggressiveness often remain unclear because of a lack of contrast enhancement. Previous studies indicated that large neutral amino acid tracers accumulate in most brain tumors, including low-grade gliomas, probably because of changes of endothelial and blood-brain barrier function. We describe 11C-methionine uptake measured… CONTINUE READING
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