Corpus ID: 212488770

1158-1161 Lovelyn Joseph 317

@inproceedings{Joseph201311581161LJ,
  title={1158-1161 Lovelyn Joseph 317},
  author={L. Joseph and E. Rejeesh and Rao Sudarshanram Narayan},
  year={2013}
}
INTRODUCTION With multinational companies turning into herbal business, online availability and regulatory bodies all over the world licensing them as dietary supplements without enough toxicological and interaction analysis data, there was drastic increase in use of herbal preparations which raise concern about their toxic and interactive propensity. This study analyzes the interaction of Valeriana wallichii (Indian valerian) and Phenobarbitone on anticonvulsant activity in maximal… Expand

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TLDR
This book is a translation of all 380 monographs on medicinal herbs published by the German commission E, an expert multidisciplinary group within the German federal health agency charged with evaluating the safety and efficacy of herbal medications. Expand
6-Methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS
TLDR
This paper is the first report of the presence of 2S(-)-hesperidin in valeriana and describes that it has sedative and sleep-enhancing properties, and 6-methylapigenin (MA) was found to have anxiolytic properties and was able to potentiate the sleep- enhancing properties of hesperidIn (HN). Expand
The NIH Anticonvulsant Drug Development ( ADD ) Program : preclinical anticonvulsant screening project
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This chapter discusses safety issues involving Chinese herbal medicine, kava, and pharmacovigilance of herbal medicines, as well as investigating the impact of quality issues on the safety of herbal products. Expand
ANTICONVULSANT ACTIVITY OF HYRDROETHANOLIC EXTRACT OF VALERIANA WALLICHII ROOT ON MAXIMAL ELECTROSHOCK INDUCED SEIZURE MODEL IN SWISS ALBINO MICE
TLDR
Hydroethanolic extract of Valeriana wallichii root showed a dose dependant reduction of hind limb tonic extensor phase in comparison with standard and control groups which was statistically significant, indicating potential antiepileptic effect on grand mal type of epilepsy in man. Expand
Pharmacological investigation of certain Valeriana officinalis L. extracts.
TLDR
The roots of Valeriana officinalis were extracted by various solvent extraction procedures and the fractions prepared were tested for their biological activity in an attempt to isolate the most active constituents, which showed some ability to potentiate the pentobarbital sleeping time in rats and showed greater hypotensive properties than V103. Expand
Assessing subjective and psychomotor effects of the herbal medication valerian in healthy volunteers
TLDR
The data suggest that acute administration of valerian does not have mood-altering or psychomotor/cognitive effects in young healthy volunteers, and Diazepam, though, produced subjective effects as measured by four different rating scales, and impaired psychom motor/c cognitive performance. Expand
Central nervous depressant activity of valerenic Acid in the mouse.
TLDR
It can be concluded, that valerenic acid has aspecific central nervous depressent properties and should be taken into account when considering the sedative action of Valerian preparations. Expand
Could Valerian Have Been the First Anticonvulsant?
TLDR
To assess the available evidence for the belief that valerian, highly recommended in the past for treating epilepsy, possessed real anticonvulsant effectiveness. Expand
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