11-cis vitamin A in dark-adapted rod outer segments is a probable source of prosthetic groups for rhodopsin biosynthesis

Abstract

THROUGHOUT life, the outer segments of rod photoreceptors (ROS) are renewed continually1, a process that entails assembly of new disk membranes at the base of the ROS. Biosynthesis of the apoprotein of rhodopsin, the major membrane protein of the ROS disks, is known to occur in several stages in the inner segment2–5. Bok has found, however, that completion… (More)
DOI: 10.1038/259247a0

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