1097 - the Cytotoxic Effect of Methotrexate Loaded Bone Cement on the Osteosarcoma Cell Lines


Introduction Polymethylmethacrylate bone cement has been frequently used as an adjunctive material in the limb salvage surgery for malignant bone tumors. The purpose of this study is to investigate the feasibility of bone cement as a vehicle of methotrexate for local treatment of osteosarcoma, and the cytotoxic effect of the eluted methotrexate on the… (More)


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