102 Surfactant and N-acetylcysteine Stimulate the Hyaluronan Synthesis by Human Fetal Lung Fibroblasts

Lung hyaluronan (HA) concentration has been found to increase in rabbit pups treated with oxygen (Ped Res 1992;32: 635 & 1994;35:280), and in premature monkeys with respiratory distress syndrome (RDS) (Ped Res 1994;35:238-43). The mechanism behind this increase is unknown.AIM: To determine if surfactant and N-acetylcysteine, used in the treatment of RDS… CONTINUE READING