10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-induced Angiogenesis in Human Umbilical Vein Endothelial Cells

Abstract

Vascular endothelial growth factor (VEGF) is reported to be a potent pro-angiogenic factor that plays a pivotal role in both physiological and pathological angiogenesis. Royal jelly (RJ) is a honeybee product containing various proteins, sugars, lipids, vitamins and free amino acids. 10-Hydroxy-2-decenoic acid (10HDA), a major fatty acid component of RJ, is… (More)
DOI: 10.1093/ecam/nem152

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@inproceedings{Izuta200910Hydroxy2decenoicAA, title={10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-induced Angiogenesis in Human Umbilical Vein Endothelial Cells}, author={Hiroshi Izuta and Yuichi Chikaraishi and Masamitsu Shimazawa and Satoshi Mishima and Hideaki Hara}, booktitle={Evidence-based complementary and alternative medicine : eCAM}, year={2009} }