1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore.

@article{Borgstahl199514AS,
  title={1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore.},
  author={Gloria E O Borgstahl and David R. Williams and Elizabeth D. Getzoff},
  journal={Biochemistry},
  year={1995},
  volume={34 19},
  pages={6278-87}
}
A photosensing protein directs light energy captured by its chromophore into a photocycle. The protein's structure must accommodate the photocycle and promote the resulting chemical or conformational changes that lead to signal transduction. The 1.4 A crystallographic structure of photoactive yellow protein, determined by multiple isomorphous replacement methods, provides the first view at atomic resolution of a protein with a photocycle. The alpha/beta fold, which differs from the original… CONTINUE READING