1-substituted 5-aminotetrazoles: syntheses from CNN3 with primary amines.

@article{Joo20081substituted5S,
  title={1-substituted 5-aminotetrazoles: syntheses from CNN3 with primary amines.},
  author={Young-Hyuk Joo and Jean'ne M Shreeve},
  journal={Organic letters},
  year={2008},
  volume={10 20},
  pages={4665-7}
}
1-Substituted 5-aminotetrazoles were prepared in situ by an excellent reaction of cyanogen azide and primary amines to generate an imidoyl azide as an intermediate in acetonitrile/water. After cyclization, the intermediate gave 1-substituted aminotetrazole in good yield. This protocol also was utilized in the syntheses of bis- and tris(1-substituted 5… CONTINUE READING