1-methylguanosine-deficient tRNA of Salmonella enterica serovar Typhimurium affects thiamine metabolism.

@article{Bjrk20031methylguanosinedeficientTO,
  title={1-methylguanosine-deficient tRNA of Salmonella enterica serovar Typhimurium affects thiamine metabolism.},
  author={Glenn R. Bj{\"o}rk and Kristina Nilsson},
  journal={Journal of bacteriology},
  year={2003},
  volume={185 3},
  pages={750-9}
}
In Salmonella enterica serovar Typhimurium a mutation in the purF gene encoding the first enzyme in the purine pathway blocks, besides the synthesis of purine, the synthesis of thiamine when glucose is used as the carbon source. On carbon sources other than glucose, a purF mutant does not require thiamine, since the alternative pyrimidine biosynthetic (APB… CONTINUE READING